Tom McDonnell

Tom is an accomplished life sciences executive whose career in commercial leadership spans more than 20 years. He has held key roles at Shire, where he was the Vice President and General Manager of Vyvanse and Intuniv, and most recently served as Chief Commercial Officer at Neos Therapeutics. Tom possesses deep commercial experience in product launch, sales, marketing, and market access. Over the past 6 years, Tom has led the strategic growth and expansion of Benchworks, including the integration of multiple business units under the agency.

Tom holds a BA from Muhlenberg College 

Alexandra Daley

Alexandra is an experienced partner to biotech and pharma, with a focus on driving commercialization and brand success. She is a trusted advisor and strategic marketer with over 25 years of delivering insight-driven solutions. Her leadership has shaped impactful strategies that enable sustainable brand differentiation, activate customers, and drive engagement across the entire product lifecycle. A proven life sciences partner, she specializes in rare disease commercialization—partnering with clients to launch, scale, and lead.

AD is known for her deep commitment to collaboration, and thrives on building strong, trust-based partnerships to bring bold ideas to life.

Alexandra holds a BA from Fairfield University.

Select Achievements

  • Led successful commercialization of 6+ rare disease therapies, including first-in-class gene therapies
  • Developed breakthrough brand strategies for over 15 clients, resulting in increase in brand preference and accelerated market penetration.
  • Developed and managed cross-functional internal teams, creating trust-based leadership approach that delivered exceptional client outcomes and 65% growth in new accounts.

Jess Podgajny

Jess is a seasoned leader passionate about partnering with established and emerging pharma and biotech organizations to catalyze growth and maximize product launch potential.

In her 20+ years as a management consultant partnering with pharmaceutical companies, Jess has led transformational initiatives for global teams in Sales, Marketing, Operations, Strategy, C-Suite, Supply Chain, and HR. 

Jess holds a BA from Penn State University. 

Greg Lief

Greg founded Asymmetry Group in early 2017 with the mission to provide a differentiated consulting experience to innovative healthcare companies. Greg has devoted 25+ years to growing healthcare companies through industry and management consulting experience, with a particular focus on helping companies launch new therapeutics. Prior to founding Asymmetry, Greg ran Global Commercial Operations at Biogen, and also held leadership positions in Corporate Strategy at Life Technologies and Supply Chain Strategy at Wyeth Biopharma. Greg also spent a decade in strategic management consulting at Monitor Group (now Deloitte Consulting), serving biopharmaceutical, medical device, diagnostic and life science clients. Greg holds an M.B.A. from the Kellogg School of Management at Northwestern University, and a B.A. in Biology and Environmental Studies from Dartmouth College. When he’s not serving clients, you can usually find Greg with his wife and two daughters skiing, climbing and biking in the White Mountains.

Yakir Siegal

Yakir joined Asymmetry Group after serving at Deloitte Consulting as a Managing Director in the Monitor Deloitte Strategy practice. He has worked in a variety of industries since originally joining Monitor Group in 1994, working on corporate and business unit strategy, commercial capability building, marketing and organic growth strategy, stakeholder management, new business development, leadership development, and organizational design. Yakir’s 20+ years of experience in life sciences spans a broad range of therapeutic areas and covers the full spectrum of the product lifecycle, from early commercial input through brand revitalization and lifecycle management. Yakir is a co-author of several articles on topics, including drug pricing and market access, a return on capital view of the US healthcare industry, and the role of business model innovation in MedTech. Yakir received an A.B., A.M., and Ph.D. in Physics from Harvard University, where his research focused on ultrafast laser spectroscopy, semiconductor physics, and nonlinear optics. Yakir and his wife live in Brookline and enjoy traveling around New England and visiting or being visited by their two daughters.